sulfadoxine - PMC

Result Filters

You searched 8+ million full text articles

Try this search in 34+ million citations and abstracts

PMC Full-Text Search Results

Items: 1 to 20 of 7692

<< First< Prev

Page of 385

Next >Last >>

Select item 59231811.

Population Pharmacokinetic Properties of Sulfadoxine and Pyrimethamine: a Pooled Analysis To Inform Optimal Dosing in African Children with Uncomplicated Malaria

Miné de Kock, Joel Tarning, Lesley Workman, Elizabeth N. Allen, Mamadou M. Tekete, Abdoulaye A. Djimde, David J. Bell, Steve A. Ward, Karen I. Barnes, Paolo Denti

Antimicrob Agents Chemother. 2018 May; 62(5): e01370-17. Prepublished online 2018 Feb 20. Published online 2018 Apr 26. doi: 10.1128/AAC.01370-17

PMCID:: PMC5923181

Article PDF–3.3M

Select item 54045782.

Optimal Antimalarial Dose Regimens for Sulfadoxine-Pyrimethamine with or without Azithromycin in Pregnancy Based on Population Pharmacokinetic Modeling

Sam Salman, Francisca Baiwog, Madhu Page-Sharp, Susan Griffin, Harin A. Karunajeewa, Ivo Mueller, Stephen J. Rogerson, Peter M. Siba, Kenneth F. Ilett, Timothy M. E. Davis

Antimicrob Agents Chemother. 2017 May; 61(5): e02291-16. Prepublished online 2017 Feb 27. Published online 2017 Apr 24. doi: 10.1128/AAC.02291-16

PMCID:: PMC5404578

Article PDF–1.5M

Select item 55713263.

Assessment of Clinical Pharmacokinetic Drug-Drug Interaction of Antimalarial Drugs α/β-Arteether and Sulfadoxine-Pyrimethamine

Y. S. Chhonker, V. V. Bhosale, S. K. Sonkar, H. Chandasana, D. Kumar, S. Vaish, S. C. Choudhary, S. Bhadhuria, S. Sharma, R. K. Singh, G. K. Jain, A. K. Vaish, S. P. S. Gaur, R. S. Bhatta

Antimicrob Agents Chemother. 2017 Sep; 61(9): e02177-16. Prepublished online 2017 Jul 3. Published online 2017 Aug 24. doi: 10.1128/AAC.02177-16

PMCID:: PMC5571326

Article PDF–535K

Select item 73039574.

Overall, anti-malarial, and non-malarial effect of intermittent preventive treatment during pregnancy with sulfadoxine-pyrimethamine on birthweight: a mediation analysis

Michelle E Roh, Feiko O ter Kuile, Francois Rerolle, M Maria Glymour, Stephen Shiboski, Roly Gosling, Julie Gutman, Abel Kakuru, Meghna Desai, Richard Kajubi, Anne L'Ianziva, Moses R Kamya, Grant Dorsey, R Matthew Chico

Lancet Glob Health. 2020 Jul; 8(7): e942–e953. Published online 2020 Jun 17. doi: 10.1016/S2214-109X(20)30119-4

PMCID:: PMC7303957

Article

Select item 55297355.

Pharmacokinetics of Sulfadoxine and Pyrimethamine for Intermittent Preventive Treatment of Malaria During Pregnancy and After Delivery

M de Kock, J Tarning, L Workman, MM Nyunt, I Adam, KI Barnes, P Denti

CPT Pharmacometrics Syst Pharmacol. 2017 Jul; 6(7): 430–438. Published online 2017 Jun 9. doi: 10.1002/psp4.12181

Correction in:: CPT Pharmacometrics Syst Pharmacol. 2020 Apr; 9(4): 238–239.

Correction in:: CPT Pharmacometrics Syst Pharmacol. 2020 Sep; 9(9): 542.

Correction in:: CPT Pharmacometrics Syst Pharmacol. 2021 Feb; 10(2): 174.

PMCID:: PMC5529735

Article PDF–496K

Select item 71688636.

Effect of sulfadoxine-pyrimethamine doses for prevention of malaria during pregnancy in hypoendemic area in Tanzania

Wigilya P. Mikomangwa, Omary Minzi, Ritah Mutagonda, Vito Baraka, Eulambius M. Mlugu, Eleni Aklillu, Appolinary A. R. Kamuhabwa

Malar J. 2020; 19: 160. Published online 2020 Apr 19. doi: 10.1186/s12936-020-03234-4

PMCID:: PMC7168863

Article PDF–1.0M

Select item 65171487.

Mefloquine for preventing malaria in pregnant women

Raquel González, Clara Pons‐Duran, Mireia Piqueras, John J Aponte, Feiko O ter Kuile, Clara Menéndez, Cochrane Infectious Diseases Group

Cochrane Database Syst Rev. 2018; 2018(11): CD011444. Published online 2018 Nov 14. doi: 10.1002/14651858.CD011444.pub3

PMCID:: PMC6517148

Article PDF–1.0M

Select item 58750658.

Mefloquine for preventing malaria in pregnant women

Raquel González, Clara Pons‐Duran, Mireia Piqueras, John J Aponte, Feiko O ter Kuile, Clara Menéndez

Cochrane Database Syst Rev. 2018; 2018(3): CD011444. Published online 2018 Mar 21. doi: 10.1002/14651858.CD011444.pub2

Update in:: Cochrane Database Syst Rev. 2018; 2018(11): CD011444.

PMCID:: PMC5875065

Article PDF–1020K

Select item 45803629.

Distribution of Plasmodium vivaxpvdhfr and pvdhps alleles and their association with sulfadoxine–pyrimethamine treatment outcomes in Indonesia

Puji B. S. Asih, Sylvia S. Marantina, Rodiah Nababan, Neil F. Lobo, Ismail E. Rozi, Wajio Sumarto, Rita M. Dewi, Sekar Tuti, Ahmad S. Taufik, Mulyanto, Robert W. Sauerwein, Din Syafruddin

Malar J. 2015; 14: 365. Published online 2015 Sep 22. doi: 10.1186/s12936-015-0903-0

PMCID:: PMC4580362

Article PDF–1.1M

Select item 893391310.

Predicting the effect of sulfadoxine-pyrimethamine uptake by pregnant women on birth weight using a generalized ordered partial proportional odds model

Chris Guure, Seth Afagbedzi

BMC Pregnancy Childbirth. 2022; 22: 223. Published online 2022 Mar 19. doi: 10.1186/s12884-022-04565-7

PMCID:: PMC8933913

Article PDF–1.2M

Select item 320981611.

Limited Geographical Origin and Global Spread of Sulfadoxine-Resistant dhps Alleles in Plasmodium falciparum Populations

Toshihiro Mita, Meera Venkatesan, Jun Ohashi, Richard Culleton, Nobuyuki Takahashi, Takahiro Tsukahara, Mathieu Ndounga, Lek Dysoley, Hiroyoshi Endo, Francis Hombhanje, Marcelo U. Ferreira, Christopher V. Plowe, Kazuyuki Tanabe

J Infect Dis. 2011 Dec 15; 204(12): 1980–1988. Published online 2011 Oct 21. doi: 10.1093/infdis/jir664

PMCID:: PMC3209816

Article PDF–644K

Select item 183198112.

Pharmacokinetic interactions between chloroquine, sulfadoxine and pyrimethamine and their bioequivalence in a generic fixed-dose combination in healthy volunteers in Uganda

C Obua, M S Ntale, MS Lundblad, M Mahindi, LL Gustafsson, JW Ogwal-Okeng, W W Anokbonggo, U Hellgren

Afr Health Sci. 2006 Jun; 6(2): 86–92.

PMCID:: PMC1831981

Article PDF–240K

Select item 229136613.

Population pharmacokinetics of chloroquine and sulfadoxine and treatment response in children with malaria: suggestions for an improved dose regimen

Celestino Obua, Urban Hellgren, Muhammed Ntale, Lars L Gustafsson, Jasper W Ogwal-Okeng, Toufigh Gordi, Markus Jerling

Br J Clin Pharmacol. 2008 Apr; 65(4): 493–501. Published online 2008 Feb 20. doi: 10.1111/j.1365-2125.2007.03050.x

PMCID:: PMC2291366

Article PDF–1001K

Select item 737729114.

Interactions Between Antenatal Sulfadoxine-Pyrimethamine, Drug-Resistant Plasmodium falciparum Parasites, and Delivery Outcomes in Malawi

Steve M Taylor, Brandt Levitt, Betsy Freedman, Mwayiwawo Madanitsa, Kyaw-Lay Thwai, Linda Kalilani-Phiri, Carole Khairallah, Victor Mwapasa, Feiko O ter Kuile, Steven R Meshnick

J Infect Dis. 2020 Aug 15; 222(4): 661–669. Published online 2020 Mar 28. doi: 10.1093/infdis/jiaa145

PMCID:: PMC7377291

Article PDF–1.2M

Select item 41560915.

Sulfadoxine Resistance in Plasmodium vivax Is Associated with a Specific Amino Acid in Dihydropteroate Synthase at the Putative Sulfadoxine-Binding Site

Michael Korsinczky, Katja Fischer, Nanhua Chen, Joanne Baker, Karl Rieckmann, Qin Cheng

Antimicrob Agents Chemother. 2004 Jun; 48(6): 2214–2222. doi: 10.1128/AAC.48.6.2214-2222.2004

PMCID:: PMC415609

Article PDF–533K

Select item 786669116.

Low prevalence of highly sulfadoxine‐resistant dihydropteroate synthase alleles in Plasmodium falciparum isolates in Benin

Samaly Souza Svigel, Adicath Adeothy, Augustin Kpemasse, Ernest Houngbo, Antoine Sianou, Ramani Saliou, Monica E. Patton, Fortune Dagnon, Eric S. Halsey, Alexis Tchevoede, Venkatachalam Udhayakumar, Naomi W. Lucchi

Malar J. 2021; 20: 72. Published online 2021 Feb 5. doi: 10.1186/s12936-021-03605-5

PMCID:: PMC7866691

Article PDF–1.0M

Select item 531908217.

Changing the policy for intermittent preventive treatment with sulfadoxine–pyrimethamine during pregnancy in Malawi

Chikondi A. Mwendera, Christiaan de Jager, Herbert Longwe, Kamija Phiri, Charles Hongoro, Clifford M. Mutero

Malar J. 2017; 16: 84. Published online 2017 Feb 20. doi: 10.1186/s12936-017-1736-9

PMCID:: PMC5319082

Article PDF–1.2M

Select item 502127118.

Scheduled Intermittent Screening with Rapid Diagnostic Tests and Treatment with Dihydroartemisinin-Piperaquine versus Intermittent Preventive Therapy with Sulfadoxine-Pyrimethamine for Malaria in Pregnancy in Malawi: An Open-Label Randomized Controlled Trial

Mwayiwawo Madanitsa, Linda Kalilani, Victor Mwapasa, Anna M. van Eijk, Carole Khairallah, Doreen Ali, Cheryl Pace, James Smedley, Kyaw-Lay Thwai, Brandt Levitt, Duolao Wang, Arthur Kang’ombe, Brian Faragher, Steve M. Taylor, Steve Meshnick, Feiko O. ter Kuile

PLoS Med. 2016 Sep; 13(9): e1002124. Published online 2016 Sep 13. doi: 10.1371/journal.pmed.1002124

PMCID:: PMC5021271

Article PDF–5.1M

Select item 539994019.

Sulfadoxine-Pyrimethamine Exhibits Dose-Response Protection Against Adverse Birth Outcomes Related to Malaria and Sexually Transmitted and Reproductive Tract Infections

R. Matthew Chico, Enesia Banda Chaponda, Cono Ariti, Daniel Chandramohan

Clin Infect Dis. 2017 Apr 15; 64(8): 1043–1051. Published online 2017 Mar 2. doi: 10.1093/cid/cix026

Correction in:: Clin Infect Dis. 2017 Jun 1; 64(11): 1635.

PMCID:: PMC5399940

Article PDF–157K

Select item 741639120.

Impact of intermittent preventive treatment of malaria in pregnancy with dihydroartemisinin-piperaquine versus sulfadoxine-pyrimethamine on the incidence of malaria in infancy: a randomized controlled trial

Abel Kakuru, Prasanna Jagannathan, Richard Kajubi, Teddy Ochieng, Harriet Ochokoru, Miriam Nakalembe, Tamara D. Clark, Theodore Ruel, Sarah G. Staedke, Daniel Chandramohan, Diane V. Havlir, Moses R. Kamya, Grant Dorsey

BMC Med. 2020; 18: 207. Published online 2020 Aug 10. doi: 10.1186/s12916-020-01675-x

PMCID:: PMC7416391

Article PDF–697K

<< First< Prev

Page of 385

Next >Last >>

Supplemental Content

Filter your results:

Manage Filters

PMC Images search for sulfadoxine

Fig. 3

Effects of various concentrations of drugs on Plasmodium falciparum oocyst density. A) Effects of different Sulfadoxine concentrations on oocyst distributions in mosquitoes. B) Effects of different Pyrimethamine concentrations on oocyst distributions in mosquitoes. C) Effects of different Sulfadoxine462 pyrimethamine concentrations on oocyst distributions in mosquitoes. S, sulfadoxine; P, pyrimethamine; SP, sulfadoxine-pyrimethamine; SD3 = sulfadoxine concentration equivalent to serum levels of sulfadoxine at day 3 following an oral dose of sulfadoxine-pyrimethamine; SD7, sulfadoxine concentration equivalent to serum levels of sulfadoxine at day 7 following an oral dose of sulfadoxine466 pyrimethamine; SD14, sulfadoxine concentration equivalent to serum levels of sulfadoxine at day 14 following an oral dose of sulfadoxine-pyrimethamine; idem for PD3, PD7, PD14, SPD3, SPD7 and SPD14.

Sulfadoxine-pyrimethamine impairs Plasmodium falciparum gametocyte infectivity and Anopheles mosquito survival

Int J Parasitol. ;40(10):1221-1228.
FIG. 3.

(A) Stick representation overlay of the putative sulfadoxine-binding sites from P. falciparum and P. vivax DHPS. Sulfadoxine is shown in green stick form with its electron densities as small dots. All amino acids shown in thick (contact residue associated with resistance) or thin stick form are predicted contact residues with the exception of K540/K512 and A581/A553. S436/S382 (red), A437/A383 (red), A613/V585 (blue), K540/K512 (orange), and A581/A553 (orange) are all associated with P. falciparum resistance to sulfadoxine. Innate resistance to sulfadoxine in P. vivax is predicted to be a consequence of the V585 residue. (B) Stick representation of the putative binding site in DHPS from P. falciparum for sulfadoxine. The mutations S436F, A437G, and A613S associated with resistance by P. falciparum to sulfadoxine have been shown to demonstrate their potential effects on the binding site.

Sulfadoxine Resistance in Plasmodium vivax Is Associated with a Specific Amino Acid in Dihydropteroate Synthase at the Putative Sulfadoxine-Binding Site

Antimicrob Agents Chemother. 2004 Jun;48(6):2214-2222.
Fig. 1

Sulfadoxine, pyrimethamine or sulfadoxine-pyrimethamine pressure, mosquito feeding and oocyst measurement days are shown for each experimental design. A) Impact of Sulfadoxine, pyrimethamine or sulfadoxine-pyrimethamine on gametocytogenesis induction; B) impact of Sulfadoxine, pyrimethamine or sulfadoxine-pyrimethamine on gametocyte maturation; C) impact of Sulfadoxine, pyrimethamine or sulfadoxine-pyrimethamine on gametocyte infectivity.

Sulfadoxine-pyrimethamine impairs Plasmodium falciparum gametocyte infectivity and Anopheles mosquito survival

Int J Parasitol. ;40(10):1221-1228.
Figure 1

Pooled chloroquine (A) and sulfadoxine (B) concentrations vs. time

Population pharmacokinetics of chloroquine and sulfadoxine and treatment response in children with malaria: suggestions for an improved dose regimen

Br J Clin Pharmacol. 2008 Apr;65(4):493-501.